The former Manchester United and Real Madrid striker has stepped down from his role after just one season at the Dutch club.
Ruud van Nistelrooy has vacated his role as PSV Eindhoven manager with immediate effect.
Following talks with the board of directors on Tuesday, Van Nistelrooy resigned from his job, citing a lack of support within the club as his reason for leaving. The 46-year-old informed the PSV players and coaching staff of his decision on Wednesday morning.
“PSV regrets Van Nistelrooy’s decision and is grateful to him for winning the Johan Cruyff Scale and the TOTO KNVB Cup this season and hopes to close the football year with second place,” read a club statement.
Van Nistelrooy took charge of the first team last July after Roger Schmidt’s departure. He had spent a number of years coaching the youth teams at PSV and working with the Dutch national team before then.
In 50 matches across all competitions, Van Nistelrooy oversaw 34 victories, eight draws, and eight defeats. He led PSV to two trophies, the Johan Cruyff Scale and the TOTO KNVB Cup.
His assistant, Fred Rutten, will take charge of the club for Sunday’s final game of the season against AZ Alkmaar.
PSV sit second in the Eredivisie standings, with 72 points from 33 games. They are 10 points behind champions Feyenoord, but three ahead of third-placed Ajax.