Having secured a commanding win in the reverse fixture last week, Ole Gunnar Solskjaer’s men will now aim to get the job done with ease.
15 teams will face disappointment while 15 others will continue their journey in Europe by the end of a Thursday night that will serve as a decider of fates.
Tottenham have already booked a place in the Europa League last-16 following an 8-1 aggregate win over Austrian outfit Wolfsberger AC.
They will be joined by half of the 30 teams that take to the pitch tonight, one of which could either be Manchester United or Real Sociedad.
Manchester United sealed a 4-0 victory in the first leg, courtesy of a Bruno Fernandes brace and strikes from Marcus Rashford and Daniel James, and have a very strong case for advancing to the next round.
Manchester United vs Real Sociedad Form:
The hosts had a good warm for their return to Europe as they beat Newcastle United 3-1 in the Premier League last time out.
The win at Old Trafford saw them extend their unbeaten streak to seven matches across all competitions.
Ole Gunnar Solskjaer’s men have scored at least thrice in their last four home games and have failed to find the net only once in their last 11 outings at home soil.
A slight cause of concern is that they have not managed three wins in succession since December, although an upset in the upcoming match seems unlikely.
The Royals, meanwhile, bounced back after their last-32 first-leg drubbing by thrashing Alaves 4-0 at home in La Liga.
They will hope to put a similar performance on Thursday night in the hope of causing an upset. If not that, at least to go on the back of a good result when they face Real Madrid on Monday.
Manchester United vs Real Sociedad Head-to-head:
Manchester United vs Real Sociedad Team News:
Donny van de Beek, Scott McTominay, Edinson Cavani are unavailable for the Red Devils. Paul Pogba and Phil Jones are also out injured.
Robin Le Normand will the match due to the accumulation of bookings. Luca Sangalli is out injured while Aritz Elustondo and Joseba Zaldua are also likely to miss out.
Manchester United: Henderson; Williams, Bailly, Tuanzebe, Telles; Fred, Matic; James, Mata, Rashford; Greenwood
Real Sociedad: Remiro; Gorosabel, Zubeldia, Sagnan, Monreal; Zubimendi, Merino, Silva; Portu, Isak, Oyarzabal