The Red Devils striker suffered an injury while being on Uruguay duty.
Manchester United will face Leicester City in their first game after the international break on Saturday. The Red Devils hope to leapfrog Tottenham from fifth place on the table. However, they will have to play without one of their key forwards against the Foxes.
Edinson Cavani, who suffered an injury in Uruguay’s World Cup qualifier against Chile last week, will not play for the Red Devils in the upcoming game. Ralf Rangnick confirmed the striker’s injury in a pre-match interview on Friday.
He told MUTV: “Yeah, they all seem to be fit. The only player who is injured, unfortunately again, is Edinson Cavani.
“In his second game [with Uruaguay], he had to be substituted after 25 minutes with some calf problems.
“According to the doctor, he will be out for a couple of weeks, four weeks, maybe even five weeks. So we have to wait and see.”
Cavani has played only 614 minutes of Premier League football this season, scoring two goals. The Uruguayan star is among the players expected to leave the club next summer, with the English giants reportedly hoping to sign a new striker.