Leicester missed out on a Champions League spot for a second straight season as Tottenham came from behind to claim a 4-2 victory.
Jamie Vardy twice put the Foxes ahead from the penalty spot, but Kane, a Kasper Schmeichel own goal and two late Gareth Bale strikes secured Spurs a Europa League Conference play-off spot. The Foxes finish fifth in the table, with Liverpool and Chelsea filling the final two top-four places for a Champions League spot.
Harry Kane was named in the Spurs side for their trip to the King Power for what could be the final time.
The England striker is keen to leave this summer but started as Spurs chased a top-six berth. Interim boss Ryan Mason made two changes, with Davinson Sanchez and Matt Doherty coming in.
Leicester made the first move of the afternoon as they took a 17th-minute lead thanks to Vardy’s penalty.
Referee Anthony Taylor originally waved away protests after Vardy went down under Toby Alderweireld’s challenge, but VAR advised him to look at the pitchside monitor and he changed his decision. The striker calmly sent Hugo Lloris the wrong way.
Kane went ahead in the race for the Premier League’s Golden Boot as he levelled for Spurs just four minutes before the break.
The England striker lashed home Son Heung-min’s deflected cross to score his 22nd goal of the season, moving ahead of Mohamed Salah.
The Foxes were back in front seven minutes into the second period when Vardy went down under a challenge from Davinson Sanchez. The Foxes hitman dusted himself down before beating a static Lloris down from the spot.
But Tottenham were level again with 14 minutes to go after a disastrous error from Schmeichel. The Foxes stopper tried to punch out a corner but ended up finding his own net instead.
And a rampant Spurs went ahead in the 87th minute when Kane did brilliantly to go round Schmeichel and keep the ball alive, before a pullback found sub Bale to slot in from the edge of the area. VAR checked for a handball against Kane, but the goal was given.
Bale was at it again in stoppage-time when he danced through the Foxes backline and clipped a strike against the post before sweeping in the rebound.
Player ratings
Leicester City: Schmeichel (5), Soyuncu (7), Fofana (5), Castagne (5), Thomas (6), Albrighton (6), Ndidi (6), Tielemans (5), Madisson (5), Vardy (7), Iheanacho (6),
Tottenham: Lloris (6), Doherty (6), Sanchez (5), Alderweireld (6), Reguilon (6), Hojbjerg (6), Winks (7), Bergwijn (6), Alli (6), Son (6), Kane (7)
Substitute: Bale (8)
Feel free to make your pick on player’s ratings and performances using the widget below.